Description: The antibody recognizes CD117/c-kit which is a member of the Tryosine Kinase Receptor family and is highly homologous to both PDGF and CSF-1 receptors. CD117 is useful in differentiating gastrointestinal stromal tumors for leiomyosarcomas which are histologically similar neoplasms with different biological behaviors as well as a marker for mast cell tumors.
Catalog: VeteMAbXXX
Species Reactivity: Canine, Feline
Source: Rabbit Polyclonal
Antigen: Proprietary
Positive Control: Mast cells or gastrointestinal stromal tumors
References
- Dailey, D.D., Ehrhart, E.J., Duval, D.L., Bass, T. and Powers, B.E. DOG1 is a sensitive and specific immunohistochemical marker for diagnosis of canine gastrointestinal stromal tumors. J Vet Diagn Invest. 2015;27(3):268-277. [PMID 25862711]